Which statement about blade type for glycol methacrylate is most accurate according to the material?

• A. Steel blades are commonly used
• B. Cast iron blades are standard
• C. Glass blades are typically used
• D. Diamond knives are the only option

Answer: (C)

The material asks you to consider what blade material works best with glycol methacrylate during microtomy. Glycol methacrylate is a plastic resin that cuts cleanly with a sharp edge but doesn’t require the extreme stiffness of epoxy resins. A glass blade is typically used because it provides a very smooth, consistent edge that yields clean ribbons, is economical, and interacts well with this resin. Steel blades tend to dull more quickly and can leave impressions in the cut, while cast iron blades are not standard due to edge irregularities and rust risk. Diamond knives are excellent for very hard resins or ultrathin sections intended for electron microscopy, but they’re expensive and not the routine choice for standard GMA work. Therefore, glass blades are the most accurate choice for glycol methacrylate.