Which pigment fails to be demonstrated when KMnO4 is used as the oxidizing agent in Gomori Burtner technique?

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Multiple Choice

Which pigment fails to be demonstrated when KMnO4 is used as the oxidizing agent in Gomori Burtner technique?

Explanation:
KMnO4 is a strong oxidizer used in this technique to bleach certain pigments. Melanin, the dark pigment in tissues, is susceptible to oxidation by permanganate, which disrupts its color and makes it disappear under the staining method. Because of this, melanin cannot be demonstrated when KMnO4 is the oxidizing agent. The other options are not decolorized in the same way under these conditions (lipofuscin and hemosiderin can still be demonstrated with this approach), and Nissl substance is not a pigment addressed by this oxidation-based demonstration.

KMnO4 is a strong oxidizer used in this technique to bleach certain pigments. Melanin, the dark pigment in tissues, is susceptible to oxidation by permanganate, which disrupts its color and makes it disappear under the staining method. Because of this, melanin cannot be demonstrated when KMnO4 is the oxidizing agent. The other options are not decolorized in the same way under these conditions (lipofuscin and hemosiderin can still be demonstrated with this approach), and Nissl substance is not a pigment addressed by this oxidation-based demonstration.

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