Which fixative is used for bone marrow sections and must be washed out with running water?

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Multiple Choice

Which fixative is used for bone marrow sections and must be washed out with running water?

Explanation:
Bone marrow sections are often fixed with mercury-containing fixatives, such as Zenker's or Helly's. These fixatives preserve cellular and nuclear detail very well, but the mercury salts left behind can interfere with stains and cause artifacts if not removed. Washing the tissue in running water after fixation flushes out the mercuric salts and other residual fixative, reducing staining artifacts and toxicity before dehydration and embedding. That rinsing step is why Zenker and Helly are the best choices for this requirement.

Bone marrow sections are often fixed with mercury-containing fixatives, such as Zenker's or Helly's. These fixatives preserve cellular and nuclear detail very well, but the mercury salts left behind can interfere with stains and cause artifacts if not removed. Washing the tissue in running water after fixation flushes out the mercuric salts and other residual fixative, reducing staining artifacts and toxicity before dehydration and embedding. That rinsing step is why Zenker and Helly are the best choices for this requirement.

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