The Oil Red O control slide corresponds to which tissue type?

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Multiple Choice

The Oil Red O control slide corresponds to which tissue type?

Explanation:
Oil Red O is a fat-soluble dye that highlights neutral lipids, especially triglycerides, but it requires frozen sections because routine processing dissolves lipids. To have a reliable positive control, you want a tissue with abundant neutral lipid droplets. Fatty liver (hepatic steatosis) fits perfectly because hepatocytes accumulate large lipid droplets that readily take up Oil Red O and appear bright red, demonstrating the stain’s capability. The other tissues shown don’t normally contain lipid droplets to the same extent in a way that would reliably produce the characteristic red staining, so they’re not ideal positive controls for this stain.

Oil Red O is a fat-soluble dye that highlights neutral lipids, especially triglycerides, but it requires frozen sections because routine processing dissolves lipids. To have a reliable positive control, you want a tissue with abundant neutral lipid droplets. Fatty liver (hepatic steatosis) fits perfectly because hepatocytes accumulate large lipid droplets that readily take up Oil Red O and appear bright red, demonstrating the stain’s capability. The other tissues shown don’t normally contain lipid droplets to the same extent in a way that would reliably produce the characteristic red staining, so they’re not ideal positive controls for this stain.

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