The issue in the image can most likely be corrected by which action?

• A. Reembedding the tissue
• B. Rehydrating the tissue
• C. Staining with hematoxylin
• D. Dehydrating further

Answer: (A)

When the issue stems from improper embedding or infiltration, creating a new, well-infiltrated block is the fix. Reembedding involves removing the tissue from the current block, completely deparaffinizing and rehydrating it, reprocessing through the standard solvents, and embedding it in fresh paraffin with the tissue oriented correctly. This restores stable contact between tissue and paraffin, improves sectioning quality, and reduces artifacts such as chatter, folds, or poor adherence that come from a poorly prepared original block.

Rehydrating would only reintroduce water for staining and won’t solve embedding or infiltration defects. Dehydrating further removes more water and likewise doesn’t address block integrity. Staining with hematoxylin colors nuclei but doesn’t fix physical embedding issues. So reembedding directly targets the structural problem and leads to better sections.