The Gomori method reveals which pair of cells inside the pancreatic islet?

• A. Alpha and beta cells
• B. Delta and gamma cells
• C. Acinar and duct cells
• D. Endothelial and stellate cells

Answer: (A)

The Gomori method is used to highlight certain endocrine cell granules within the pancreatic islets, making it possible to distinguish the hormone-producing cell types there. In the islets, alpha cells produce glucagon and beta cells produce insulin, and these two cell types contain granules that react to this staining, so they stand out distinctly. Exocrine components like acinar and duct cells don’t have the same granule content and aren’t highlighted by this method, and the delta and gamma cells aren’t the pair preferentially revealed by this stain. So this technique best reveals the alpha and beta cells inside the pancreatic islet.