Nissl substance is present in which cells?

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Multiple Choice

Nissl substance is present in which cells?

Explanation:
Nissl substance are clusters of rough endoplasmic reticulum with ribosomes located in the neuron cell body and dendrites, visible with basic dyes as basophilic granules. This reflects the high rate of protein synthesis neurons need to maintain neurotransmitter production and membrane components. Erythrocytes lack a nucleus and organelles, so they do not have rough ER or Nissl bodies. Glial cells and fibroblasts do possess rough ER, but the conspicuous Nissl bodies are a feature of neurons, not these other cell types, so their staining patterns do not show the dense Nissl substance seen in neuron soma.

Nissl substance are clusters of rough endoplasmic reticulum with ribosomes located in the neuron cell body and dendrites, visible with basic dyes as basophilic granules. This reflects the high rate of protein synthesis neurons need to maintain neurotransmitter production and membrane components. Erythrocytes lack a nucleus and organelles, so they do not have rough ER or Nissl bodies. Glial cells and fibroblasts do possess rough ER, but the conspicuous Nissl bodies are a feature of neurons, not these other cell types, so their staining patterns do not show the dense Nissl substance seen in neuron soma.

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