Luxol Fast Blue staining is used to demonstrate which tissue component?

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Multiple Choice

Luxol Fast Blue staining is used to demonstrate which tissue component?

Explanation:
Luxol Fast Blue specifically binds to the lipids in the myelin sheath, so it highlights myelinated fibers in blue. This makes it ideal for assessing myelin distribution and demyelination in CNS tissue, such as in multiple sclerosis models. In practice, it’s often used with a counterstain (like cresyl violet) to also visualize Nissl substance in neuronal cell bodies on the same slide. The other options don’t fit because Nissl substance is stained by cresyl violet, astrocytes require different markers or stains, and nuclei aren’t specifically targeted by Luxol Fast Blue.

Luxol Fast Blue specifically binds to the lipids in the myelin sheath, so it highlights myelinated fibers in blue. This makes it ideal for assessing myelin distribution and demyelination in CNS tissue, such as in multiple sclerosis models. In practice, it’s often used with a counterstain (like cresyl violet) to also visualize Nissl substance in neuronal cell bodies on the same slide. The other options don’t fit because Nissl substance is stained by cresyl violet, astrocytes require different markers or stains, and nuclei aren’t specifically targeted by Luxol Fast Blue.

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