Hyaluronidase is used to digest some connective tissue mucins.

• A. True
• B. False
• C. Only glycosaminoglycans
• D. It digests proteins

Answer: (A)

Hyaluronidase works by breaking down the extracellular polysaccharide network that gives connective tissue its gel-like consistency. Its main target is hyaluronic acid, a major glycosaminoglycan that forms a key part of connective tissue mucins. By cleaving these hyaluronic acid chains, the enzyme reduces the viscosity and integrity of the mucin matrix, allowing tissue components to diffuse and be processed more effectively. Since mucins in connective tissue are rich in these mucopolysaccharide chains, hyaluronidase is used to digest them. It does not digest proteins, so option stating it digests proteins isn’t correct.