Gomori's Aldehyde Fuchsin demonstrates which tissue components?

• A. Elastic and mast cells
• B. Amyloid
• C. Reticulin
• D. Nissl substance

Answer: (A)

Gomori’s aldehyde fuchsin is a metachromatic stain that highlights elastic tissue and mast cells. It binds to elastin, staining elastic fibers a bright red to purple color, and it also colors the granules of mast cells distinctly, making both components stand out against surrounding tissue. This staining behavior helps identify tissues rich in elastic fibers and the presence of mast cells. Amyloid requires Congo red to visualize, reticulin is typically shown with silver-based reticulin stains, and Nissl substance is demonstrated with Nissl stains like cresyl violet, not with aldehyde fuchsin.