Formalin pigment would most certainly be formed when the pH of the formalin is which value?

Prepare for the Histotechnologist Certification Exam with our comprehensive study material. Use flashcards, detailed explanations, and intuitive multiple-choice questions. Boost your test readiness and achieve certification success!

Multiple Choice

Formalin pigment would most certainly be formed when the pH of the formalin is which value?

Explanation:
Formalin pigment forms when the fixative is acidic. In acidic formalin, formaldehyde reacts with heme to produce acid hematin, a brown-black pigment that deposits in tissue. Neutral or basic fixatives do not promote this reaction, so pigment formation is unlikely there. So the condition that would most certainly yield pigment is the most acidic pH value among the options, whereas the other, less acidic (more neutral or basic) values would not. To prevent this pigment, use buffered formalin at a neutral pH.

Formalin pigment forms when the fixative is acidic. In acidic formalin, formaldehyde reacts with heme to produce acid hematin, a brown-black pigment that deposits in tissue. Neutral or basic fixatives do not promote this reaction, so pigment formation is unlikely there. So the condition that would most certainly yield pigment is the most acidic pH value among the options, whereas the other, less acidic (more neutral or basic) values would not. To prevent this pigment, use buffered formalin at a neutral pH.

More Multiple Choice Questions
Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy