Fixation in Helly solution will preserve erythrocytes.

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Multiple Choice

Fixation in Helly solution will preserve erythrocytes.

Explanation:
Mercury-containing fixatives preserve erythrocytes well. Helly’s solution combines a mercuric chloride fixative with formaldehyde and acetic acid, and the mercuric chloride rapidly cross-links and stabilizes proteins. This strong protein stabilization prevents autolysis and preserves the delicate structure of red blood cells, so their morphology remains intact through processing and staining.

Mercury-containing fixatives preserve erythrocytes well. Helly’s solution combines a mercuric chloride fixative with formaldehyde and acetic acid, and the mercuric chloride rapidly cross-links and stabilizes proteins. This strong protein stabilization prevents autolysis and preserves the delicate structure of red blood cells, so their morphology remains intact through processing and staining.

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