A method that can be used to demo senile plaques is that of

• A. Bielschowsky
• B. Cajal
• C. Weil
• D. Nissl

Answer: (A)

Bielschowsky silver staining is used to demonstrate senile plaques. This method impregnates tissue with silver so that amyloid plaques and neurofibrillary tangles appear as dark deposits under light microscopy, making it a reliable way to visualize these Alzheimer's-related features in brain sections. Nissl staining highlights neuronal cell bodies and does not reveal plaques, while Golgi/Cajal methods emphasize neuronal morphology rather than specific amyloid deposits. The Weil stain is not a standard choice for showing senile plaques, so Bielschowsky stands out as the appropriate technique.