A good control for glycogen demonstration is which organ?

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Multiple Choice

A good control for glycogen demonstration is which organ?

Explanation:
Glycogen demonstration with PAS staining relies on tissues that have a large, uniform store of glycogen in their cells. The liver is the best choice because hepatocytes normally contain abundant glycogen packed in the cytoplasm, producing a strong, consistent PAS-positive signal. This makes it a reliable reference to confirm that the staining procedure is working properly. In contrast, tissues like brain and kidney have little glycogen, and heart muscle has glycogen but in a less uniform, less predictable pattern, so they don’t provide the same dependable control.

Glycogen demonstration with PAS staining relies on tissues that have a large, uniform store of glycogen in their cells. The liver is the best choice because hepatocytes normally contain abundant glycogen packed in the cytoplasm, producing a strong, consistent PAS-positive signal. This makes it a reliable reference to confirm that the staining procedure is working properly. In contrast, tissues like brain and kidney have little glycogen, and heart muscle has glycogen but in a less uniform, less predictable pattern, so they don’t provide the same dependable control.

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